[HTML][HTML] The role of CXCR3 and its chemokine ligands in skin disease and cancer

PT Kuo, Z Zeng, N Salim, S Mattarollo, JW Wells… - Frontiers in …, 2018 - frontiersin.org
murine model of obliterative bronchiolitis (48). In this study the authors demonstrated that
blockade of CXCR3 reduced airway obliteration … with CXCR3 can selectively induce regulatory

[HTML][HTML] Differential role of CXCR3 in inflammation and colorectal cancer

JD Abron, NP Singh, AE Murphy, MK Mishra, RL Price… - Oncotarget, 2018 - ncbi.nlm.nih.gov
… Further, in some murine models, global CXCR3 inhibition … the divergent roles of CXCR3
and its ligands on the induction of … CXCR3 and its ligands influence the TME by regulating

[HTML][HTML] Overview of the mechanisms that may contribute to the non-redundant activities of interferon-inducible CXC chemokine receptor 3 ligands

M Metzemaekers, V Vanheule, R Janssens… - Frontiers in …, 2018 - frontiersin.org
… and regulatory mechanisms of IFN-induced CXCR3 ligands, and propose that their in vivo
… the presence of the other in a murine model of obliterative bronchiolitis (196). Nevertheless, …

Neutrophil chemoattractant receptors in health and disease: double-edged swords

M Metzemaekers, M Gouwy, P Proost - Cellular & molecular …, 2020 - nature.com
regulatory mechanisms, which may, at least partially, explain … in a murine model of allergic
asthma. Finally, a pivotal … , eg, CCRs and CXCR3. Prolonged stimulation or exposure to high …

IFNγ-induced chemokines are required for CXCR3-mediated T-cell recruitment and antitumor efficacy of anti-HER2/CD3 bispecific antibody

J Li, R Ybarra, J Mak, A Herault, P De Almeida… - Clinical Cancer …, 2018 - AACR
… The expression of CXCR3 can be regulated by TCR … treatment through CXCR3 and its
cognate chemokine ligands. … We used a genetically engineered murine model harboring human …

CXCR3+ monocytes/macrophages are required for establishment of pulmonary metastases

KL Butler, E Clancy-Thompson, DW Mullins - Scientific reports, 2017 - nature.com
… , and (3) the production of CXCR3 ligands in the lung is induced by … murine model of
metastatic-like melanoma to demonstrate a defect in engraftment of lungs in the absence of CXCR3

[HTML][HTML] … endothelial growth factor receptors 1 and 2 attenuates natural killer cell and innate immune responses in an experimental model for obliterative bronchiolitis

R Krebs, JM Tikkanen, A Raissadati, M Hollmén… - The American Journal of …, 2022 - Elsevier
… for down-regulation of NK cell stress ligand receptor Klrk1 … However, with the obliterative
changes in tracheal allografts … allograft bronchioles, the mouse heterotopic allograft model is …

IL-17A is critical for CD8+ T effector response in airway epithelial injury after transplantation

R Zhang, H Fang, R Chen, JC Ochando, Y Ding… - …, 2018 - journals.lww.com
… is closely correlated with obliterative bronchiolitis development. In … and in vivo neutralization
of CXCR3 or its ligands inhibits the … of bronchiolitis obliterans syndrome in a murine model of …

Chronic lung allograft dysfunction: a systematic review of mechanisms

PJ Royer, G Olivera-Botello, A Koutsokera… - …, 2016 - journals.lww.com
… double-strand RNA 14 results in obliterative bronchiolitis. … the development of bronchiolitis
obliterans in a mouse model of … The presence of CXCR3 ligands 9 or inflammatory cytokines …

[HTML][HTML] The biology of chronic graft-versus-host disease: a task force report from the National Institutes of Health Consensus Development Project on Criteria for …

KR Cooke, L Luznik, S Sarantopoulos, FT Hakim… - Biology of Blood and …, 2017 - Elsevier
… We discuss the role of the thymus in chronic GVHD, although its role in adult recipients …
Depletion of regulatory T cells (Tregs) or reduction of their suppressor function by calcineurin …